Ir-catalyzed almost perfect enantioselective synthesis of helical polyaryls based on an axially-chiral sequence.
نویسندگان
چکیده
Ir-catalyzed enantioselective [2 + 2 + 2] cycloaddition of tetraynes or an octayne with monoalkynes proceeded to give helically-chiral quinquearyl and noviaryl compounds, which respectively have four and eight consecutive axial chiralities, in an almost enantiomerically pure form.
منابع مشابه
Synthesis of novel axially chiral Rh-NHC complexes derived from BINAM and application in the enantioselective hydrosilylation of methyl ketones.
Novel axially chiral Rh N-heterocyclic carbene complexes were prepared from axially dissymmetric 1,1'-binaphthalenyl-2,2'-diamine and applied in the Rh-catalyzed enantioselective hydrosilylation of methyl ketones. The corresponding sec-alcohols can be obtained in high yields with good to excellent ee.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 شماره
صفحات -
تاریخ انتشار 2005